| Name | Meaning | Gender | Origin |
|---|
| Dixie | Abbreviation of Richard. In the USA Dixie refers to the French word for ten: also to the southern states below the Mason- Dixon line.
| Female | Latin |
| Dock | 7Th Son Of The 7Th Son | Unisex | English |
| Dolly | Variant of the Greek Dorothy meaning Gift of God.
| Female | English |
| Donna | Lady
| Female | Italian |
| Doodlebug | | Female | |
| Duchess | From the AristoCats
| Female | |
| Dundee | after the Marmelade | Male | Scottish |
| E.T. | Extra Terrestrial | Unisex | |
| Ebony and Ivory | | Unisex | Hebrew |
| Eclipse | | Unisex | Hebrew |
| Edgar | Fortunate and powerful.
| Male | |
| Edison | Son of Edward
| Male | English |
| Edmundo | Blessed Guardian | Male | Portuguese |
| Edwardo | Prosperous guardian.
| Male | |
| Efrain | Doubly fruitful. Form of Hebrew Ephraim
| Male | Spanish |
| Efren | Doubly fruitful. Form of Hebrew Ephraim
| Male | |
| Elbertina | Noble
| Female | |
| Elmo | protector | Male | Italian |
| Elsie | pledged to God | Female | English |
| Emily | named after Emily Bronte and Emily Dickinson | Female | English |
| Eureka | | Male | Hebrew |
| Eurypides | | Unisex | Hebrew |
| Evanglista | | Female | |
| Exodus | | Male | Hebrew |
| Fabien | Derived from the Roman clan name Fabius
| Male | |