| Name | Meaning | Gender | Origin |
|---|
| Rocky | rest | Male | English |
| Rosie | From Rose - The most beautiful of flowers | Female | English |
| Sabbath | | Unisex | |
| Sable | A carnivorous mammal of Northern Europe with soft, dark fur. | Female | Animal |
| Sabrina | Legendary princess
| Female | Celtic |
| Salem | Peace
| Male | Hebrew |
| Salty | | Unisex | Hebrew |
| Samantha | A listener | Female | Hebrew |
| Sammy | Hebrew, told by God | Male | English |
| Santana | Little Saint | Female | Spanish |
| Satan | The Devil and adversary of God | Male | |
| Satin | smooth, shiny | Female | |
| Satin | smooth, shiny | Female | |
| Shade | | Male | |
| Shadow | A rough, dark image cast by an object blocking the sun's rays | Female | English |
| Shady | | Unisex | |
| Sharpie | | Unisex | |
| Sheba | from Sheba | Female | Hebrew |
| Silhouette | | Unisex | Hebrew |
| Silky | Soft as silk. | Unisex | |
| Sirius | burning | Male | Latin |
| Sky | The expanse of air over the Earth | Female | Nature |
| Skye | sky, sheltering | Female | Scottish |
| Skylar | eternal life, strength, love and beauty | Female | Spelling |
| Smokey | A grayish blue colour. Slang for highway patrol officer | Male | |