| Name | Meaning | Gender | Origin |
|---|
| Salome | Asked of God | Female | Hebrew |
| Sam | to hear | Male | English |
| Samara | after the character in The Ring movie | Female | Hebrew |
| Samwise | Lord of the Rings | Unisex | |
| Santa | after the novel by Federico Gamboa | Female | Feminine |
| Sargent | officer, to serve | Male | Spelling |
| Sassafras | | Male | Hebrew |
| Sausage | Chopped meat stuffed into a prepared casing and cooked. | Unisex | |
| Scotch | Scotch whiskey. | Unisex | |
| Scout | One dispatched from main body to gather information | Male | Word |
| Seamus | supplanter | Male | Irish |
| Selene | after the Greek godess of the moon | Unisex | |
| Selma | godly helmet | Female | |
| Severus | stern | Male | Latin |
| Shamus | Supplanter | Male | Anglicized |
| Shiloh | tranquil | Female | Biblical |
| Shiraz | | Unisex | |
| Shy | | Unisex | |
| Sibyl | seer, oracle | Female | Greek |
| Sigmund | Victory: protection. Austrian psychologist Sigmund Freud.
| Male | |
| Sir | | Unisex | Hebrew |
| Snowy | Covered with snow | Unisex | |
| Solomon | Wise and peaceful | Male | Hebrew |
| Spooky | | Unisex | |
| Spunky | Spirited, plucky. | Male | |