| Name | Meaning | Gender | Origin |
|---|
| Sid | | Unisex | |
| Sienna | A clay like earthy reddish brown | Female | Italian |
| Silvia | from the woods | Female | Latin |
| Simon | he who hears | Male | Hebrew |
| Simone | one who hears | Female | |
| Singer | | Unisex | Hebrew |
| Siren | | Unisex | |
| Skinner | | Unisex | Hebrew |
| Skyler | Dutch, scholar | Male | Spelling |
| Smith | blacksmith | Male | English |
| Somchai | | Unisex | |
| Sookie | lily | Female | English |
| Sophie | Wisdom. Variant of Sophia
| Female | |
| Special | | Unisex | Hebrew |
| Spencer | Shopkeeper, dispenser, keeper | Male | English |
| Stackhouse | | Unisex | Hebrew |
| Stacy | Greek, feminine variation of Anastasios, resurrection | Female | English |
| Stan | after the South Park character Stan Marsh | Male | Short |
| Star | A celestial body that emits light. A famous performer. | Female | Word |
| Star | A celestial body that emits light. A famous performer. | Female | Word |
| Stars | and Stripes | Unisex | |
| Stephanie | garland, crown | Female | Greek |
| Stephen | crown | Male | Greek |
| Sterling | British money or coin. A type of silver. Of good character. genuine, valued | Male | English |
| Steve | garland, crown | Male | English |