| Name | Meaning | Gender | Origin |
|---|
| Roxanne | Dawn
| Female | Persian |
| Roxy | From Roxanne - Brilliant dawn | Female | English |
| Ruby | Jewel
| Female | Latin |
| Rusty | Covered in rust - a brownish red colour. | Unisex | |
| Sabrina | Legendary princess
| Female | Celtic |
| Sadie | Princess
| Female | English |
| Saffron | A cooking spice | Female | Spice |
| Sapphire | Precious Gem | Female | Hebrew |
| Sassy | Lively and spirited | Female | |
| Savannah | From the open plain
| Female | Spanish |
| Scooter | One who goes suddenly and speedily. | Male | |
| Selma | godly helmet | Female | |
| Shadow | A rough, dark image cast by an object blocking the sun's rays | Female | English |
| Shannon | wise one, river name | Female | Irish |
| Sheena | God's gift
| Female | Anglicization |
| Shelley | clearing on a bank | Male | English |
| Smokey | A grayish blue colour. Slang for highway patrol officer | Male | |
| Smokey | A grayish blue colour. Slang for highway patrol officer | Male | |
| Smokey | A grayish blue colour. Slang for highway patrol officer | Male | |
| Snickers | A brand of candy bar. | Unisex | |
| Snickers | A brand of candy bar. | Unisex | |
| Sparrow | a bird | Female | Nature |
| Splash | To cause fluid to scatter in flying masses. To display very noticeably. | Unisex | |
| Squeaky | | Unisex | |
| Starr | Star | Female | English |