| Name | Meaning | Gender | Origin |
|---|
| Roxie | Persian, dawn | Female | English |
| Roy | regal one, Red haired | Male | |
| Royal | kingly, royal | Male | |
| Royce | son of the king | Male | English |
| Ruby | Jewel
| Female | Latin |
| Ruff | Fun spelling of rough; irregular surface or boisterous. | Unisex | |
| Rufus | Red haired | Male | Latin |
| Sadie | Princess
| Female | English |
| Sage | Aromatic grayish-green herb. Wise or experienced person. | Female | |
| Sailor | One who serves in the navy or works on a ship. | Male | Occupational |
| Salome | Asked of God | Female | Hebrew |
| Samson | Bright sun
| Male | Hebrew |
| Sanders | Alexander's son
| Male | |
| Sandler | after the actor Adam Sandler | Unisex | |
| Savannah | From the open plain
| Female | Spanish |
| Sawyer | woodsman | Male | English |
| Scarlet | Scarlet coloured, deep red | Female | Color |
| Scarlett | Red | Female | English |
| Schuyler | scholar | Male | Dutch |
| Selene | after the Greek godess of the moon | Unisex | |
| Selina | Moon | Unisex | Greek |
| Selma | godly helmet | Female | |
| Serena | Tranquil or serene. | Female | Latin |
| Shade | | Male | |
| Sharp | | Unisex | Hebrew |