| Name | Meaning | Gender | Origin |
|---|
| Roz | Rose | Female | Polish |
| Ruff | Fun spelling of rough; irregular surface or boisterous. | Unisex | |
| Ruth | compassionate friend | Female | Hebrew |
| Sage | Aromatic grayish-green herb. Wise or experienced person. | Female | |
| Saint | | Unisex | Hebrew |
| Scar | from The Lion King | Unisex | |
| Scud | | Unisex | Hebrew |
| Shaq | | Unisex | Hebrew |
| Shark | | Unisex | |
| Shine | | Unisex | Hebrew |
| Sid | | Unisex | |
| Sir | | Unisex | Hebrew |
| Skip | From Skipper, Meaning Shipmaster | Unisex | English |
| Sky | The expanse of air over the Earth | Female | Nature |
| Skye | sky, sheltering | Female | Scottish |
| Slash | | Unisex | |
| Slim | Slender in proportion to height. | Unisex | |
| Smoke | | Unisex | |
| Smoke | | Unisex | |
| Smooch | | Unisex | |
| Sniff | A short inhale through the nose. To savour or investigate a smell. | Unisex | |
| Snoop | To pry into the private affairs of others | Unisex | |
| Snow | Frozen crystals that fall in soft, white flakes | Female | English |
| Socks | Short stockings finishing above the ankle | Unisex | |
| Song | | Unisex | Hebrew |