| Name | Meaning | Gender | Origin |
|---|
| Sir | | Unisex | Hebrew |
| Skeet | speedy | Male | English |
| Skip | From Skipper, Meaning Shipmaster | Unisex | English |
| Sky | The expanse of air over the Earth | Female | Nature |
| Skye | sky, sheltering | Female | Scottish |
| Slash | | Unisex | |
| Slate | | Male | |
| Slick | | Male | |
| Slim | Slender in proportion to height. | Unisex | |
| Sly | One who is cunning, tricky and crafty. | Male | English |
| Smith | blacksmith | Male | English |
| Smoke | | Unisex | |
| Smoke | | Unisex | |
| Smooch | | Unisex | |
| Smudge | A blotch or smear | Male | |
| Sniff | A short inhale through the nose. To savour or investigate a smell. | Unisex | |
| Snoop | To pry into the private affairs of others | Unisex | |
| Snow | Frozen crystals that fall in soft, white flakes | Female | English |
| Socks | Short stockings finishing above the ankle | Unisex | |
| Song | | Unisex | Hebrew |
| Sox | Short stockings finishing above the ankle | Unisex | |
| Sox | Short stockings finishing above the ankle | Unisex | |
| Spark | | Unisex | |
| Specs | | Unisex | Hebrew |
| Spike | A long, thick sharp-pointed piece of wood or metal | Male | American |