| Name | Meaning | Gender | Origin |
|---|
| Sabrina | Legendary princess
| Female | Celtic |
| Scourge | | Unisex | |
| Sekhmet | | Unisex | |
| Selene | after the Greek godess of the moon | Unisex | |
| Seuss | | Unisex | |
| Sheila | blind one | Female | Irish |
| Shogun | Hereditary ruler and commander of Japanese army | Unisex | |
| Siren | | Unisex | |
| Sparta | | Unisex | |
| Sphinx | | Unisex | |
| Styx | from Greek mythology, the river that formed the boundary between earth and the underworld | Unisex | |
| Tao | Philosophy and religion of China. | Unisex | |
| Thalia | blooming, plentiful | Female | Greek |
| Tyr | Viking mythology: the god of war | Unisex | |