| Name | Meaning | Gender | Origin |
|---|
| Sibyl | seer, oracle | Female | Greek |
| Sky | The expanse of air over the Earth | Female | Nature |
| Skylar | eternal life, strength, love and beauty | Female | Spelling |
| Snowball | | Unisex | |
| Snowy | Covered with snow | Unisex | |
| Solstice | Sun Exposure | Female | Greek |
| Sooty | Covered with soot | Unisex | |
| Sophia | Wisdom.
| Female | Greek |
| Sparkle | To shine with animation | Unisex | |
| Spice | Plant used to flavour food or beverages. | Unisex | |
| Spirit | Part of the human being associated with the mind. Vigorous or animated state - spirited. Also distilled alcohol. | Female | Word |
| Spook | | Unisex | |
| Spooky | | Unisex | |
| Spring | spring season | Female | Word |
| Sprinkles | | Unisex | |
| Star | A celestial body that emits light. A famous performer. | Female | Word |
| Star | A celestial body that emits light. A famous performer. | Female | Word |
| Stardust | | Female | |
| Steed | | Unisex | |
| Sugar | A sweet powder from sugar cane. Slang for sweetheart. | Female | Literary |
| Sugar | A sweet powder from sugar cane. Slang for sweetheart. | Female | Literary |
| Sweetness | | Unisex | Hebrew |
| Swizzle | | Unisex | Hebrew |
| Sybil | prophetess | Female | Greek |
| Tabitha | gazelle, roe-buck | Female | Aramaic |