| Name | Meaning | Gender | Origin |
|---|
| Shaggy | Bushy and matted (hair), unkempt. | Unisex | |
| Sheldon | protected hill | Male | English |
| Shilo | | Unisex | |
| Shiloh | tranquil | Female | Biblical |
| Shogun | Hereditary ruler and commander of Japanese army | Unisex | |
| Sidney | Saint Denis | Female | |
| Sigmund | Victory: protection. Austrian psychologist Sigmund Freud.
| Male | |
| Simeon | God is listening | Male | Hebrew |
| Sirius | burning | Male | Latin |
| Skip | From Skipper, Meaning Shipmaster | Unisex | English |
| Smoky | | Unisex | |
| Snoopy | | Male | |
| Socrates | | Male | |
| Solomon | Wise and peaceful | Male | Hebrew |
| Spencer | Shopkeeper, dispenser, keeper | Male | English |
| Spike | A long, thick sharp-pointed piece of wood or metal | Male | American |
| Steve | garland, crown | Male | English |
| Stonewall | | Unisex | Hebrew |
| Stubby | | Unisex | |
| Sultan | A ruler of a Moslem country | Male | Swahili |
| Susanna | lily | Female | Hebrew |
| Sydney | from city of St. Denis | Female | |
| Ted | English, wealthy guardian | Male | English |
| Teddy | From Edward - Prosperous guardian | Unisex | |
| Thaddeus | Praise be to God | Male | Aramaic |