| Name | Meaning | Gender | Origin |
|---|
| Dice | Small cubes with sides numbered 1 to 6 used in games. | Male | Word |
| Dinky | dog on National Lampoon's Vacation | Unisex | |
| Disney | | Unisex | Hebrew |
| Dotty | From Dorothy - Gift of God. Also covered in dots. Another meaning is amusingly eccentric or absurd. | Unisex | |
| Dragon | Dragon, Fire Breathing Creature | Unisex | English |
| Dusty | Covered with dust, tinged with grey | Unisex | |
| Eartha Kitt | | Unisex | Hebrew |
| Eatbugs | | Unisex | Hebrew |
| Edward | Guardian
| Male | English |
| Elmyra | Noble | Unisex | English |
| Elvis | Elf-wise friend. Variant of Alvin. Made famous by singer and actor Elvis Presley.
| Male | Meaning |
| Eric The Cat | | Unisex | Hebrew |
| Esmerelda | Emerald, Jewel | Unisex | Spanish |
| Eureka | | Male | Hebrew |
| Faron | handsome servant | Male | English |
| Fat Cat | | Unisex | Hebrew |
| Felina Feral | | Unisex | Hebrew |
| Felix | Lucky
| Male | Latin |
| Felix the Cat | cartoon character | Unisex | |
| Fellini | | Unisex | Hebrew |
| Figaro | | Male | Hebrew |
| Flip | Lover Of Horses | Unisex | English |
| Fluff | | Unisex | Hebrew |
| Fluffy | Covered with fluff, Soft, light and airy. | Unisex | |
| Flyball | | Unisex | Hebrew |