| Name | Meaning | Gender | Origin |
|---|
| Snookums | | Unisex | Hebrew |
| Snooper | | Unisex | Hebrew |
| Snowball | | Unisex | |
| Snowy | Covered with snow | Unisex | |
| Socks | Short stockings finishing above the ankle | Unisex | |
| Sonia | wisdom | Female | Russian |
| Sonja | | Unisex | |
| Sparta | | Unisex | |
| Spice | Plant used to flavour food or beverages. | Unisex | |
| Spiffy | | Unisex | |
| Spook | | Unisex | |
| Spooky | | Unisex | |
| Steele | | Unisex | |
| Stewie | | Unisex | |
| Stimpy | | Unisex | Hebrew |
| Streaky | | Unisex | |
| Stubbs | | Unisex | |
| Sugar | A sweet powder from sugar cane. Slang for sweetheart. | Female | Literary |
| Sugar | A sweet powder from sugar cane. Slang for sweetheart. | Female | Literary |
| Sumo | Form of wrestling. | Unisex | |
| Susan | Lily Diminutive of Susannah also used as an independent name. In the apocryphal Book of Tobit Susannah courageously defended herself against wrongful accusation. White lilies grew in the Biblical city of Susa in Persia.
| Female | Hebrew |
| Tailspin | | Unisex | |
| Tama | Jewel | Unisex | Japanese |
| Tao | Philosophy and religion of China. | Unisex | |
| Tattoo | | Unisex | |