| Name | Meaning | Gender | Origin |
|---|
| Sarah | Princess
| Female | Hebrew |
| Sasha | defending men | Female | Russian |
| Sausage | Chopped meat stuffed into a prepared casing and cooked. | Unisex | |
| Sawyer | woodsman | Male | English |
| Scamp | A mischievous youngster | Male | |
| Scarlett | Red | Female | English |
| Sean | God's grace | Male | Irish |
| Sebastian | An august person | Male | Latin |
| Serena | Tranquil or serene. | Female | Latin |
| Serenity | peaceful | Female | Latin |
| Shadow | A rough, dark image cast by an object blocking the sun's rays | Female | English |
| Shaggy | Bushy and matted (hair), unkempt. | Unisex | |
| Shane | God is gracious | Male | Irish |
| Shaun | Irish variation of John, God is gracious | Male | Spelling |
| Sienna | A clay like earthy reddish brown | Female | Italian |
| Simon | he who hears | Male | Hebrew |
| Skittles | | Male | |
| Skittles | | Male | |
| Snowball | | Unisex | |
| Soda | A carbonated water. | Unisex | |
| Sofia | wisdom | Female | Greek |
| Sophia | Wisdom.
| Female | Greek |
| Sophie | Wisdom. Variant of Sophia
| Female | |
| Squirt | Slang for a small person | Unisex | |
| Stacey | Greek, fruitful, productive | Male | Greek |