| Name | Meaning | Gender | Origin |
|---|
| Shadow | A rough, dark image cast by an object blocking the sun's rays | Female | English |
| Shilo | | Unisex | |
| Shiloh | tranquil | Female | Biblical |
| Socks | Short stockings finishing above the ankle | Unisex | |
| Sofia | wisdom | Female | Greek |
| Sophia | Wisdom.
| Female | Greek |
| Sophie | Wisdom. Variant of Sophia
| Female | |
| Sparky | Animated, lively. | Unisex | |
| Spencer | Shopkeeper, dispenser, keeper | Male | English |
| Spike | A long, thick sharp-pointed piece of wood or metal | Male | American |
| Spot | after Data's cat on Star Trek: The Next Generation | Male | |
| Spud | Slang for potato. | Male | |
| Stella | a star | Female | Latin |
| Stella | a star | Female | Latin |
| Sugar | A sweet powder from sugar cane. Slang for sweetheart. | Female | Literary |
| Sugar | A sweet powder from sugar cane. Slang for sweetheart. | Female | Literary |
| Tanner | leather worker | Male | English |
| Ted | English, wealthy guardian | Male | English |
| Teddy | From Edward - Prosperous guardian | Unisex | |
| Tilly | Mighty in war
| Female | English |
| Toby | God is Good | Male | English |
| Toto | | Unisex | |
| Tramp | To travel on foot. A vagrant. | Unisex | |
| Trapper | One who traps animals for their fur. | Unisex | |
| Trixie | she who brings happiness | Female | Latin |