| Name | Meaning | Gender | Origin |
| Bear | Large mammal with large head, bulky body and coarse thick fur | Male | Animal |
| Boomer | A large full grown kangaroo. A baby boomer. | Unisex | |
| Brady | large-chested | Male | Irish |
| Bruiser | A large heavyset man | Unisex | |
| Bull | The adult male of certain large animals like cattle and elephants | Unisex | |
| Cougar | A large powerful American mountain cat | Male | Nature |
| Crockett | large curl | Male | English |
| Jaguar | Large Spotted Feline | Male | English |
| Jumbo | Unusually large person, animal or thing e.g. Jumbo Jet. From African 'jumba' meaning elephant. | Male | |
| Kodiak | Large Alaskan brown bear. | Female | Russian |
| Kyo | Approval, Ginger, Or Large | Unisex | Japanese |
| Magna | Large | Unisex | Latin |
| Magnum | A large type of wine bottle. | Unisex | |
| Max | Large spring | Male | English |
| Max | Large spring | Male | English |
| Moose | Largest member of the deer family. Moose have heavy brown bodies with humped shoulders and broad antlers. | Unisex | |
| Paddy The Large | | Unisex | Hebrew |
| Pumpkin | Large round fruit with orange skin | Male | |
| Sahara | the moon . The world's largest desert situated in northern Africa. | Female | Arabic |
| Saturn | Sixth and second largest planet away from the Sun. | Male | |
| Talon | large claw of a bird of prey | Male | |
| Tank | A large metal container. A heavily armed combat vehicle | Unisex | |
| Tiger | A large, striped, carnivorous mammal from Asia. | Male | Animal |
| Tiger | A large, striped, carnivorous mammal from Asia. | Male | Animal |