| Name | Meaning | Gender | Origin |
|---|
| Raquel | Innocent
| Female | Spanish |
| Raven | Dark haired or wise
| Female | Word |
| Reaper | | Unisex | |
| Regan | little king | Female | Irish |
| Rhapsody | | Female | Hebrew |
| Ribbon | | Unisex | Hebrew |
| Rima | White antelope
| Female | Arabic |
| Ripper | | Unisex | |
| Rose | Flower
| Female | Latin |
| Rosemary | the rosemary plant | Female | Latin |
| Roxanne | Dawn
| Female | Persian |
| Rudi | Famous Wolf | Female | Hungarian |
| Rydia | Rose pettles on still water.
| Female | |
| Sabrina | Legendary princess
| Female | Celtic |
| Saina | Princess
| Female | |
| Samantha | A listener | Female | Hebrew |
| Samara | after the character in The Ring movie | Female | Hebrew |
| Sandi | Defender, helper of all men.
| Female | |
| Sapphire | Precious Gem | Female | Hebrew |
| Sasquatch | has extra toes and hence is a bigfoot | Unisex | |
| Sassy | Lively and spirited | Female | |
| Scarface | | Unisex | Hebrew |
| Scat Cat | | Unisex | |
| Scotty | From Scotland: a Gael. Diminutive of Scott.
| Female | English |
| Shadow | A rough, dark image cast by an object blocking the sun's rays | Female | English |