| Diva | Divine one
| Female | Latin |
| Dolores Jane Umbridge | Senior Undersecretary to Minister.
| Female | |
| Doogie Mouser | Like Doogie Howser
| Male | |
| Dorcas Meadowes | | Unisex | |
| Doris Crockford | Woman at the Leaky Cauldron.
| Female | |
| Doughnut | | Unisex | Hebrew |
| Dracula | | Unisex | Hebrew |
| Drusilla | Courageous, Valian | Female | Hebrew |
| Earnest | Serious: determined.
| Male | |
| Ebony | A tropical tree of southern Asia with hard, dark wood | Female | English |
| Eddy | Abbreviation of names beginning with Ed- like Edward and Edmond.
| Male | English |
| Edward | Guardian
| Male | English |
| Edwardo | Prosperous guardian.
| Male | |
| Ella | beautiful fairy woman, all | Female | |
| Elroy | red-haired youth.
| Male | English |
| Elvira | Mistress Of The Dark | Female | Spanish |
| Elvira | impartial judgement, close | Female | Spanish |
| Emerald | The prized green emerald gemstone.
| Female | |
| Emperor | Male ruler of an empire | Male | |
| Endora | fountain | Unisex | |
| Evanglista | | Female | |
| Evelyn | Life
| Female | English |
| Evrard | Strong as a boar
| Male | |
| Fala | Crow | Unisex | Native American |
| Falken | Surname relating to falconry.
| Male | |