| Name | Meaning | Gender | Origin |
|---|
| Sable | A carnivorous mammal of Northern Europe with soft, dark fur. | Female | Animal |
| Sadie | Princess
| Female | English |
| Saga | | Female | Hebrew |
| Samantha | A listener | Female | Hebrew |
| Sassy | Lively and spirited | Female | |
| Satin | smooth, shiny | Female | |
| Satin | smooth, shiny | Female | |
| Scarlet | Scarlet coloured, deep red | Female | Color |
| Shadow | A rough, dark image cast by an object blocking the sun's rays | Female | English |
| Shark | | Unisex | |
| Shelby | From the manor house Willow farm. English surname used more for girls than boys given names.
| Female | English |
| Sherbert | Frozen dessert made from fruit, sugar and water. Australian slang for beer. | Unisex | |
| Sigurd | Victorious Guardian | Unisex | Scandinavian |
| Smoke | | Unisex | |
| Smoke | | Unisex | |
| Snuffles | | Unisex | Hebrew |
| Sophie | Wisdom. Variant of Sophia
| Female | |
| Spirit | Part of the human being associated with the mind. Vigorous or animated state - spirited. Also distilled alcohol. | Female | Word |
| Star | A celestial body that emits light. A famous performer. | Female | Word |
| Star | A celestial body that emits light. A famous performer. | Female | Word |
| Sumo | Form of wrestling. | Unisex | |
| Swizzle | | Unisex | Hebrew |
| Tank | A large metal container. A heavily armed combat vehicle | Unisex | |
| Tara | A hill where the kings met
| Female | Irish |
| Tempest | storm | Female | Word |