| Name | Meaning | Gender | Origin |
|---|
| Serge | servant | Male | |
| Sergei | Servant | Male | Russian |
| Shane | God is gracious | Male | Irish |
| Shani | scarlet | Female | Hebrew |
| Shanna | | Female | |
| Shannon | wise one, river name | Female | Irish |
| Shaun | Irish variation of John, God is gracious | Male | Spelling |
| Shawn | God is gracious | Male | Spelling |
| Shay | gift | Male | Phonetic |
| Sheila | blind one | Female | Irish |
| Sheryl | Modern invented name, variation of Cherie, French, darling | Female | English |
| Shine | | Unisex | Hebrew |
| Shirley | country meadow | Female | English |
| Shoni | | Unisex | Hebrew |
| Sidney | Saint Denis | Female | |
| Silken | | Female | Hebrew |
| Silvio | from the sitcom The Sopranos | Male | Italian |
| Simon | he who hears | Male | Hebrew |
| Skeet | speedy | Male | English |
| Slate | | Male | |
| Sonja | | Unisex | |
| Sonny | A boy or young man. | Male | Nickname |
| Sonya | Loud.
| Female | |
| Spark | | Unisex | |
| Spencer | Shopkeeper, dispenser, keeper | Male | English |