| Name | Meaning | Gender | Origin |
|---|
| Ruby | Jewel
| Female | Latin |
| Rusty | Covered in rust - a brownish red colour. | Unisex | |
| Sadie | Princess
| Female | English |
| Sasha | defending men | Female | Russian |
| Sassy | Lively and spirited | Female | |
| Shadow | A rough, dark image cast by an object blocking the sun's rays | Female | English |
| Sheba | from Sheba | Female | Hebrew |
| Shorty | Of less than average size | Unisex | |
| Smoky | | Unisex | |
| Sophie | Wisdom. Variant of Sophia
| Female | |
| Sparky | Animated, lively. | Unisex | |
| Squirt | Slang for a small person | Unisex | |
| Stumpy | A short, thickset person | Unisex | |
| Sugar | A sweet powder from sugar cane. Slang for sweetheart. | Female | Literary |
| Sugar | A sweet powder from sugar cane. Slang for sweetheart. | Female | Literary |
| Tasha | Russian diminutive of Natalya, birthday of the Lord | Female | English |
| Teddy | From Edward - Prosperous guardian | Unisex | |
| Tinks | | Unisex | |
| Titch | Tiny | Unisex | |
| Tootsie | A girl or young woman. | Unisex | |
| Twiggy | | Unisex | |
| Twilight | | Unisex | |
| Venus | Love and Beauty
| Female | Latin |
| Zara | Arabic for dawn | Female | Hebrew |
| Zoe | life | Female | Greek |