| Name | Meaning | Gender | Origin |
|---|
| Rigby | Lives in the ruler
| Male | English |
| Ripley | after the novel and the movie The Talented Mr. Ripley | Male | English |
| Rococo | | Unisex | Hebrew |
| Romeo | pilgrim to Rome | Male | Italian |
| Rosebud | | Unisex | Hebrew |
| Ruffles | A strip of frilled fabric. Irregular | Unisex | |
| Rumi | | Unisex | |
| Sabine | Of Sabine, Italy | Unisex | French |
| Sallie | Princess | Unisex | English |
| Sandy | Abbreviation of Alexander defender of man.
| Male | Scottish |
| Scooter | One who goes suddenly and speedily. | Male | |
| Scout | One dispatched from main body to gather information | Male | Word |
| Scully | Herald
| Male | Irish |
| Simba | from The Lion King | Male | Swahili |
| Simba | lion | Male | Swahili |
| Skittles | | Male | |
| Skittles | | Male | |
| Smokey | A grayish blue colour. Slang for highway patrol officer | Male | |
| Smokey | A grayish blue colour. Slang for highway patrol officer | Male | |
| Smokey | A grayish blue colour. Slang for highway patrol officer | Male | |
| Snickers | A brand of candy bar. | Unisex | |
| Snickers | A brand of candy bar. | Unisex | |
| Snookie | | Unisex | |
| Snowball | | Unisex | |
| Snowflake | Single flake or crystal of snow. | Unisex | |