| Name | Meaning | Gender | Origin |
|---|
| Snickers | A brand of candy bar. | Unisex | |
| Sookie | lily | Female | English |
| Sootica | | Unisex | Hebrew |
| Sooty | Covered with soot | Unisex | |
| Spades | | Unisex | |
| Spider | An eight legged insect | Unisex | |
| Spike | A long, thick sharp-pointed piece of wood or metal | Male | American |
| Spirit | Part of the human being associated with the mind. Vigorous or animated state - spirited. Also distilled alcohol. | Female | Word |
| Spook | | Unisex | |
| Spookers | | Unisex | Hebrew |
| Spookey | | Unisex | Hebrew |
| Spooky | | Unisex | |
| Stephen | crown | Male | Greek |
| Storm | Storm
| Male | Word |
| Stormy | | Female | |
| Styx | from Greek mythology, the river that formed the boundary between earth and the underworld | Unisex | |
| Sweet | | Unisex | Hebrew |
| Sweets | | Unisex | Hebrew |
| Tabatha | Sweet and gentle. One who cares.
| Female | |
| Tabitha | gazelle, roe-buck | Female | Aramaic |
| Taffy | Sticky candy | Male | Welsh |
| Talisman | Something that apparently has magic power. A charm thought to bring the owner good luck. | Unisex | |
| Talon | large claw of a bird of prey | Male | |
| Tarantula | | Unisex | Hebrew |
| Tarot | | Male | Hebrew |