| Name | Meaning | Gender | Origin |
|---|
| Roxie | Persian, dawn | Female | English |
| Roxy | From Roxanne - Brilliant dawn | Female | English |
| Ruby | Jewel
| Female | Latin |
| Rusty | Covered in rust - a brownish red colour. | Unisex | |
| Sadie | Princess
| Female | English |
| Sagan | | Unisex | Hebrew |
| Samantha | A listener | Female | Hebrew |
| Santana | Little Saint | Female | Spanish |
| Sasha | defending men | Female | Russian |
| Sassy | Lively and spirited | Female | |
| Scarlett | Red | Female | English |
| Seraphina | afire, angel, seraph | Female | Hebrew |
| Shadow | A rough, dark image cast by an object blocking the sun's rays | Female | English |
| Shelby | From the manor house Willow farm. English surname used more for girls than boys given names.
| Female | English |
| Snickers | A brand of candy bar. | Unisex | |
| Snickers | A brand of candy bar. | Unisex | |
| Socks | Short stockings finishing above the ankle | Unisex | |
| Sophia | Wisdom.
| Female | Greek |
| Sophie | Wisdom. Variant of Sophia
| Female | |
| Sox | Short stockings finishing above the ankle | Unisex | |
| Sox | Short stockings finishing above the ankle | Unisex | |
| Sparky | Animated, lively. | Unisex | |
| Stella | a star | Female | Latin |
| Stella | a star | Female | Latin |
| Sugar | A sweet powder from sugar cane. Slang for sweetheart. | Female | Literary |