| Name | Meaning | Gender | Origin |
|---|
| Scooter | One who goes suddenly and speedily. | Male | |
| Scout | One dispatched from main body to gather information | Male | Word |
| Scrappy | Quarrelsome. Full of fighting spirit | Male | |
| Sexy | | Unisex | |
| Shadow | A rough, dark image cast by an object blocking the sun's rays | Female | English |
| Shamus | Supplanter | Male | Anglicized |
| Shelby | From the manor house Willow farm. English surname used more for girls than boys given names.
| Female | English |
| Sierra | Dark Feminine of Ciaran.
| Female | Spanish |
| Simba | from The Lion King | Male | Swahili |
| Simba | lion | Male | Swahili |
| Skittles | | Male | |
| Skittles | | Male | |
| Skye | sky, sheltering | Female | Scottish |
| Snickers | A brand of candy bar. | Unisex | |
| Snickers | A brand of candy bar. | Unisex | |
| Snoopy | | Male | |
| Snowball | | Unisex | |
| Sophie | Wisdom. Variant of Sophia
| Female | |
| Sparkey | | Male | Hebrew |
| Sparky | Animated, lively. | Unisex | |
| Spencer | Shopkeeper, dispenser, keeper | Male | English |
| Spike | A long, thick sharp-pointed piece of wood or metal | Male | American |
| Stella | a star | Female | Latin |
| Stella | a star | Female | Latin |
| Sugar | A sweet powder from sugar cane. Slang for sweetheart. | Female | Literary |