| Sir | | Unisex | Hebrew |
| Snickerdoodle | | Unisex | |
| Snuggles | To curl up closely, cuddle | Male | |
| Snuggles | To curl up closely, cuddle | Male | |
| Sparkle | To shine with animation | Unisex | |
| Spuds | | Unisex | Hebrew |
| Squirrel | | Unisex | |
| Sugar | A sweet powder from sugar cane. Slang for sweetheart. | Female | Literary |
| Sugar | A sweet powder from sugar cane. Slang for sweetheart. | Female | Literary |
| Tiger | A large, striped, carnivorous mammal from Asia. | Male | Animal |
| Tiger | A large, striped, carnivorous mammal from Asia. | Male | Animal |
| Toad | Amphibian related to frogs, with a broader body and rougher skin. | Unisex | |
| Trout | | Male | Hebrew |
| Turkey | | Unisex | |
| Two | | Unisex | Hebrew |
| Twyla | | Unisex | |
| Tybalt | | Unisex | |
| Valentino | strength, health | Male | Latin |
| Vienna | after the cat in a British tv comedy called Rising Damp | Female | Place-name: |
| Viper | | Unisex | Hebrew |
| Waffle | | Unisex | Hebrew |
| Walter | Powerful ruler
| Male | |
| Zing | | Unisex | Hebrew |
| Zippity | | Unisex | |