| Name | Meaning | Gender | Origin |
|---|
| Sagan | | Unisex | Hebrew |
| Sam | to hear | Male | English |
| Samantha | A listener | Female | Hebrew |
| Sammy | Hebrew, told by God | Male | English |
| Samson | Bright sun
| Male | Hebrew |
| Samuel | his name is God | Male | Hebrew |
| Sandy | Abbreviation of Alexander defender of man.
| Male | Scottish |
| Santana | Little Saint | Female | Spanish |
| Sasha | defending men | Female | Russian |
| Sassy | Lively and spirited | Female | |
| Sawyer | woodsman | Male | English |
| Scarlett | Red | Female | English |
| Scooter | One who goes suddenly and speedily. | Male | |
| Sebastian | An august person | Male | Latin |
| Seraphina | afire, angel, seraph | Female | Hebrew |
| Shadow | A rough, dark image cast by an object blocking the sun's rays | Female | English |
| Shelby | From the manor house Willow farm. English surname used more for girls than boys given names.
| Female | English |
| Sheldon | protected hill | Male | English |
| Simba | lion | Male | Swahili |
| Simba | from The Lion King | Male | Swahili |
| Simon | he who hears | Male | Hebrew |
| Smokey | A grayish blue colour. Slang for highway patrol officer | Male | |
| Smokey | A grayish blue colour. Slang for highway patrol officer | Male | |
| Smokey | A grayish blue colour. Slang for highway patrol officer | Male | |
| Snickers | A brand of candy bar. | Unisex | |