| Name | Meaning | Gender | Origin |
|---|
| Sin | | Unisex | |
| Sinister | | Unisex | Hebrew |
| Skully | | Unisex | Hebrew |
| Snickers | A brand of candy bar. | Unisex | |
| Snickers | A brand of candy bar. | Unisex | |
| Sootica | | Unisex | Hebrew |
| Sooty | Covered with soot | Unisex | |
| Spades | | Unisex | |
| Spider | An eight legged insect | Unisex | |
| Spook | | Unisex | |
| Spookers | | Unisex | Hebrew |
| Spookey | | Unisex | Hebrew |
| Spooky | | Unisex | |
| Styx | from Greek mythology, the river that formed the boundary between earth and the underworld | Unisex | |
| Sweet | | Unisex | Hebrew |
| Sweets | | Unisex | Hebrew |
| Talisman | Something that apparently has magic power. A charm thought to bring the owner good luck. | Unisex | |
| Tarantula | | Unisex | Hebrew |
| Thing | An entity or idea having it's own existence. | Unisex | |
| Thirteen | | Unisex | Hebrew |
| Thunder | Sound produced from lightning | Unisex | |
| Thunder | Sound produced from lightning | Unisex | |
| Thunder | Sound produced from lightning | Unisex | |
| Toad | Amphibian related to frogs, with a broader body and rougher skin. | Unisex | |
| Tootsie | A girl or young woman. | Unisex | |