| Name | Meaning | Gender | Origin |
|---|
| Rusty | Covered in rust - a brownish red colour. | Unisex | |
| Ruth | compassionate friend | Female | Hebrew |
| Sable | A carnivorous mammal of Northern Europe with soft, dark fur. | Female | Animal |
| Sadie | Princess
| Female | English |
| Sahara | the moon . The world's largest desert situated in northern Africa. | Female | Arabic |
| Sam | to hear | Male | English |
| Sass | Saxon | Unisex | Irish |
| Sassy | Lively and spirited | Female | |
| Seal | | Male | |
| Semi | | Unisex | Hebrew |
| Shade | | Male | |
| Shadow | A rough, dark image cast by an object blocking the sun's rays | Female | English |
| Sheridan | The Wild Man | Male | Irish |
| Sienna | A clay like earthy reddish brown | Female | Italian |
| Sir | | Unisex | Hebrew |
| Skor | | Unisex | Hebrew |
| Smoke | | Unisex | |
| Smoke | | Unisex | |
| Smokey | A grayish blue colour. Slang for highway patrol officer | Male | |
| Smokey | A grayish blue colour. Slang for highway patrol officer | Male | |
| Smokey | A grayish blue colour. Slang for highway patrol officer | Male | |
| Smudge | A blotch or smear | Male | |
| Snickers | A brand of candy bar. | Unisex | |
| Snickers | A brand of candy bar. | Unisex | |
| Solomon | Wise and peaceful | Male | Hebrew |