| Name | Meaning | Gender | Origin |
|---|
| Pumpkin | Large round fruit with orange skin | Male | |
| Puss | | Male | |
| Rascal | One that is playfully mischievous | Male | |
| Rey | King
| Male | Spanish |
| Rocky | rest | Male | English |
| Romeo | pilgrim to Rome | Male | Italian |
| Rusty | Covered in rust - a brownish red colour. | Unisex | |
| Salem | Peace
| Male | Hebrew |
| Sam | to hear | Male | English |
| Sammy | Hebrew, told by God | Male | English |
| Scaredy | | Unisex | Hebrew |
| Scooter | One who goes suddenly and speedily. | Male | |
| Sebastian | An august person | Male | Latin |
| Simba | lion | Male | Swahili |
| Simba | from The Lion King | Male | Swahili |
| Simon | he who hears | Male | Hebrew |
| Smokey | A grayish blue colour. Slang for highway patrol officer | Male | |
| Smokey | A grayish blue colour. Slang for highway patrol officer | Male | |
| Smokey | A grayish blue colour. Slang for highway patrol officer | Male | |
| Smudge | A blotch or smear | Male | |
| Snickers | A brand of candy bar. | Unisex | |
| Snickers | A brand of candy bar. | Unisex | |
| Snowball | | Unisex | |
| Snuggles | To curl up closely, cuddle | Male | |
| Snuggles | To curl up closely, cuddle | Male | |