| Name | Meaning | Gender | Origin |
|---|
| Ruby | Jewel
| Female | Latin |
| Ruger | | Unisex | |
| Rumble | | Unisex | |
| Sabra | thorny cactus; to rest | Female | Hebrew |
| Sadie | Princess
| Female | English |
| Sage | Aromatic grayish-green herb. Wise or experienced person. | Female | |
| Sagebrush | | Unisex | Hebrew |
| Sahara | the moon . The world's largest desert situated in northern Africa. | Female | Arabic |
| Saint | | Unisex | Hebrew |
| Samantha | A listener | Female | Hebrew |
| Santa | after the novel by Federico Gamboa | Female | Feminine |
| Sapphire | Precious Gem | Female | Hebrew |
| Sara | Arabic form of Sarah
| Female | English |
| Sarah | Princess
| Female | Hebrew |
| Savage | | Unisex | Hebrew |
| Savanna | From The Open Plain | Unisex | Spanish |
| Savannah | From the open plain
| Female | Spanish |
| Savoy | | Unisex | |
| Selma | godly helmet | Female | |
| Seville | | Unisex | |
| Sexton | Meaning Unknown | Unisex | English |
| Shack | | Unisex | Hebrew |
| Shannon | wise one, river name | Female | Irish |
| Sheep | Domesticated mammal breed for its wool and meat. Timid shy person, easily led. | Unisex | |
| Shelby | From the manor house Willow farm. English surname used more for girls than boys given names.
| Female | English |