| Name | Meaning | Gender | Origin |
|---|
| Scrat | | Unisex | |
| Scud | | Unisex | Hebrew |
| Sheldon | protected hill | Male | English |
| Sheriff | | Unisex | Hebrew |
| Sid | | Unisex | |
| Skinner | | Unisex | Hebrew |
| Slim | Slender in proportion to height. | Unisex | |
| Slinky | | Male | |
| Smokey | A grayish blue colour. Slang for highway patrol officer | Male | |
| Smokey | A grayish blue colour. Slang for highway patrol officer | Male | |
| Smokey | A grayish blue colour. Slang for highway patrol officer | Male | |
| Spot | after Data's cat on Star Trek: The Next Generation | Male | |
| Squirt | Slang for a small person | Unisex | |
| Stinky | | Unisex | |
| Stretch | To extend to full length. | Unisex | |
| Sulley | | Unisex | |
| Sullivan | black-eyed one | Male | Irish |
| Syndrome | after the character in the movie The Incredibles | Unisex | |
| Terry | Latin clan name of uncertain meaning | Male | English |
| Timmy | From Timothy - Honoring God | Unisex | |
| Tom | Bartender at the Leaky Cauldron.
| Male | English |
| Tony | priceless one | Male | English |
| Toy | Toy, Plaything | Unisex | English |
| Tuck | To make folds in, or to put in a snug spot. | Unisex | |
| Van | God Is Gracious | Male | English |