| Name | Meaning | Gender | Origin |
|---|
| Rumi | | Unisex | |
| Rusty | Covered in rust - a brownish red colour. | Unisex | |
| Sadie | Princess
| Female | English |
| Sake | Alcoholic beverage made from rice. | Unisex | |
| Samantha | A listener | Female | Hebrew |
| Sasha | defending men | Female | Russian |
| Sassy | Lively and spirited | Female | |
| Savannah | From the open plain
| Female | Spanish |
| Schnapps | Variety of strong liquor usually associated with Holland | Unisex | |
| Sephora | bird | Female | Hebrew |
| Shadow | A rough, dark image cast by an object blocking the sun's rays | Female | English |
| Sheba | from Sheba | Female | Hebrew |
| Sienna | A clay like earthy reddish brown | Female | Italian |
| Snickers | A brand of candy bar. | Unisex | |
| Snickers | A brand of candy bar. | Unisex | |
| Snowball | | Unisex | |
| Socks | Short stockings finishing above the ankle | Unisex | |
| Sophie | Wisdom. Variant of Sophia
| Female | |
| Spooky | | Unisex | |
| Squiggle | | Unisex | |
| Styx | from Greek mythology, the river that formed the boundary between earth and the underworld | Unisex | |
| Sugar | A sweet powder from sugar cane. Slang for sweetheart. | Female | Literary |
| Sugar | A sweet powder from sugar cane. Slang for sweetheart. | Female | Literary |
| Tallulah | leaping water | Female | Irish |
| Tazz | | Unisex | |