| Name | Meaning | Gender | Origin |
|---|
| Smoke | | Unisex | |
| Smokey | A grayish blue colour. Slang for highway patrol officer | Male | |
| Smokey | A grayish blue colour. Slang for highway patrol officer | Male | |
| Smokey | A grayish blue colour. Slang for highway patrol officer | Male | |
| Smudge | A blotch or smear | Male | |
| Snickers | A brand of candy bar. | Unisex | |
| Snickers | A brand of candy bar. | Unisex | |
| Snowball | | Unisex | |
| Snowflake | Single flake or crystal of snow. | Unisex | |
| Snuggles | To curl up closely, cuddle | Male | |
| Snuggles | To curl up closely, cuddle | Male | |
| Sonny | A boy or young man. | Male | Nickname |
| Sooty | Covered with soot | Unisex | |
| Sox | Short stockings finishing above the ankle | Unisex | |
| Sox | Short stockings finishing above the ankle | Unisex | |
| Spunky | Spirited, plucky. | Male | |
| Squirt | Slang for a small person | Unisex | |
| Star | A celestial body that emits light. A famous performer. | Female | Word |
| Star | A celestial body that emits light. A famous performer. | Female | Word |
| Stewie | | Unisex | |
| Stubby | | Unisex | |
| Stump | | Unisex | Hebrew |
| Sugar | A sweet powder from sugar cane. Slang for sweetheart. | Female | Literary |
| Sugar | A sweet powder from sugar cane. Slang for sweetheart. | Female | Literary |
| Summer | summer season | Female | Word |