| Name | Meaning | Gender | Origin |
|---|
| Ruby | Jewel
| Female | Latin |
| Ruffles | A strip of frilled fabric. Irregular | Unisex | |
| Rusty | Covered in rust - a brownish red colour. | Unisex | |
| Sabine | Of Sabine, Italy | Unisex | French |
| Sadie | Princess
| Female | English |
| Sallie | Princess | Unisex | English |
| Sally | saviour | Female | English |
| Sasha | defending men | Female | Russian |
| Sassy | Lively and spirited | Female | |
| Selena | after the goddess Selene | Female | Latinized |
| Shadow | A rough, dark image cast by an object blocking the sun's rays | Female | English |
| Shasta | | Female | |
| Sissy | A timid person | Female | English |
| Snickers | A brand of candy bar. | Unisex | |
| Snickers | A brand of candy bar. | Unisex | |
| Snookie | | Unisex | |
| Snowball | | Unisex | |
| Snowflake | Single flake or crystal of snow. | Unisex | |
| Socks | Short stockings finishing above the ankle | Unisex | |
| Sofia | wisdom | Female | Greek |
| Sonia | wisdom | Female | Russian |
| Sophia | Wisdom.
| Female | Greek |
| Sophie | Wisdom. Variant of Sophia
| Female | |
| Sorbet | | Unisex | |
| Sox | Short stockings finishing above the ankle | Unisex | |