| Name | Meaning | Gender | Origin |
|---|
| Strawberry | | Female | |
| Strider | | Unisex | Hebrew |
| Stripes | | Unisex | |
| Stripey | | Unisex | Hebrew |
| Stubby | | Unisex | |
| Stymie | | Unisex | Hebrew |
| Sugar | A sweet powder from sugar cane. Slang for sweetheart. | Female | Literary |
| Sugar | A sweet powder from sugar cane. Slang for sweetheart. | Female | Literary |
| Sunshine | Rays from the sun. Cheerfulness | Female | Word |
| Susana | Lily Variant of Hebrew Susannah. In the apocryphal Book of Tobit Susannah courageously defended herself against wrongful accusation. White lilies grew in the Biblical city of Susa in Persia.
| Female | |
| Sushi | Raw fish. | Unisex | |
| Sushi | Raw fish. | Unisex | |
| Suzy | Lily | Unisex | English |
| Sweetpea | | Unisex | Hebrew |
| Sweets | | Unisex | Hebrew |
| Swizzle | | Unisex | Hebrew |
| Sydney | from city of St. Denis | Female | |
| Sylvia | from the forest | Female | Latin |
| Symeon | Obedient | Unisex | Hebrew |
| Tabby | | Unisex | |
| Tabitha | gazelle, roe-buck | Female | Aramaic |
| Taco | A folded fried tortilla filled with meat, cheese and spices. | Unisex | |
| Tails | | Unisex | Hebrew |
| Tailspin | | Unisex | |
| Tang | | Unisex | |