| Name | Meaning | Gender | Origin |
|---|
| Sadie | Princess
| Female | English |
| Salem | Peace
| Male | Hebrew |
| Sam | to hear | Male | English |
| Samantha | A listener | Female | Hebrew |
| Samatha | God Has Heard | Unisex | English |
| Sammy | Hebrew, told by God | Male | English |
| Samson | Bright sun
| Male | Hebrew |
| Sandstorm | | Unisex | |
| Sarah | Princess
| Female | Hebrew |
| Sasha | defending men | Female | Russian |
| Sassy | Lively and spirited | Female | |
| Scamp | A mischievous youngster | Male | |
| Scaredy | | Unisex | Hebrew |
| Scooter | One who goes suddenly and speedily. | Male | |
| Scout | One dispatched from main body to gather information | Male | Word |
| Sebastian | An august person | Male | Latin |
| Shadow | A rough, dark image cast by an object blocking the sun's rays | Female | English |
| Sheba | from Sheba | Female | Hebrew |
| Simba | lion | Male | Swahili |
| Simba | from The Lion King | Male | Swahili |
| Simon | he who hears | Male | Hebrew |
| Sir Lionel | | Unisex | |
| Smokey | A grayish blue colour. Slang for highway patrol officer | Male | |
| Smokey | A grayish blue colour. Slang for highway patrol officer | Male | |
| Smokey | A grayish blue colour. Slang for highway patrol officer | Male | |