| Name | Meaning | Gender | Origin |
|---|
| Rosalie | rose | Female | |
| Rosanna | Greek or Latin version of Hannah, Hebrew, grace | Female | Combination |
| Rose | Flower
| Female | Latin |
| Rosemary | the rosemary plant | Female | Latin |
| Rover | A wanderer | Unisex | |
| Sabrina | Legendary princess
| Female | Celtic |
| Sadie | Princess
| Female | English |
| Sage | Aromatic grayish-green herb. Wise or experienced person. | Female | |
| Sahara | the moon . The world's largest desert situated in northern Africa. | Female | Arabic |
| Samantha | A listener | Female | Hebrew |
| Samara | after the character in The Ring movie | Female | Hebrew |
| Sammie | | Unisex | |
| Sandi | Defender, helper of all men.
| Female | |
| Sandra | Helper of Mankind | Female | English |
| Sarah | Princess
| Female | Hebrew |
| Sasha | defending men | Female | Russian |
| Sausage | Chopped meat stuffed into a prepared casing and cooked. | Unisex | |
| Scarlett | Red | Female | English |
| Serena | Tranquil or serene. | Female | Latin |
| Serenity | peaceful | Female | Latin |
| Shadow | A rough, dark image cast by an object blocking the sun's rays | Female | English |
| Shaggy | Bushy and matted (hair), unkempt. | Unisex | |
| Sienna | A clay like earthy reddish brown | Female | Italian |
| Snowball | | Unisex | |
| Soda | A carbonated water. | Unisex | |