| Name | Meaning | Gender | Origin |
|---|
| Spot | after Data's cat on Star Trek: The Next Generation | Male | |
| Spotty | Marked with spots | Unisex | |
| Sprinkles | | Unisex | |
| Spumoni | | Unisex | |
| Streak | | Unisex | |
| Stripe | | Unisex | |
| Stripey | | Unisex | Hebrew |
| Tabby | | Unisex | |
| Tabetha | | Unisex | |
| Tank | A large metal container. A heavily armed combat vehicle | Unisex | |
| Taz | | Male | |
| Theo | divine gift | Male | English |
| Thor | Viking mythology: the ruler of the weather | Male | Norse |
| Tiger | A large, striped, carnivorous mammal from Asia. | Male | Animal |
| Tiger | A large, striped, carnivorous mammal from Asia. | Male | Animal |
| Tigger | from Winnie the Pooh | Unisex | |
| Tigra | | Unisex | Hebrew |
| Timber | Wood used as a building material. Also timber-wolf. | Male | Nature |
| Toby | God is Good | Male | English |
| Trix | | Unisex | |
| Tuppence | British for two pence (coins) | Unisex | |
| Tuxedo | | Unisex | |
| Twinkle | | Unisex | |
| Twix | Brand of chocolate bar. | Unisex | |
| Ty | Abbreviation For Names Beginning With Ty-. | Male | English |