| Name | Meaning | Gender | Origin |
|---|
| Dandy | An elegant man. | Unisex | |
| Dapper | | Unisex | Hebrew |
| Dapple | | Unisex | Hebrew |
| Dean Martin | | Unisex | Hebrew |
| Dice | Small cubes with sides numbered 1 to 6 used in games. | Male | Word |
| DJ | | Unisex | Hebrew |
| Domino | Small, rectangular black and white blocks used in the game of dominos. | Male | Latin |
| Dot | Small mark. Short for Dorothy - Gift of God Short sound in Morse code. Abbreviation of Dorothy. | Female | English |
| Dotty | From Dorothy - Gift of God. Also covered in dots. Another meaning is amusingly eccentric or absurd. | Unisex | |
| Duchess | From the AristoCats
| Female | |
| Ducky | | Unisex | Hebrew |
| Duke | Highest ranking nobleman | Male | English |
| Ebony | A tropical tree of southern Asia with hard, dark wood | Female | English |
| Eddy | Abbreviation of names beginning with Ed- like Edward and Edmond.
| Male | English |
| Eightball | Black ball used in pool/billiards. | Unisex | |
| Elvis | Elf-wise friend. Variant of Alvin. Made famous by singer and actor Elvis Presley.
| Male | Meaning |
| Eskimo Pie | | Unisex | Hebrew |
| Fancy | Of superior grade. A notion or whim. | Female | English |
| Fancy Pants | | Unisex | Hebrew |
| Felix | Lucky
| Male | Latin |
| Figaro | | Male | Hebrew |
| Foxy | Resembling a fox. Slang for sexy | Female | Word |
| Fraidy | | Unisex | Hebrew |
| Freckles | Dotted with small brownish spots. | Unisex | |
| Frostbite | | Unisex | Hebrew |