| Name | Meaning | Gender | Origin |
|---|
| Sandy | Abbreviation of Alexander defender of man.
| Male | Scottish |
| Sarah | Princess
| Female | Hebrew |
| Sasha | defending men | Female | Russian |
| Sassy | Lively and spirited | Female | |
| Satan | The Devil and adversary of God | Male | |
| Satin | smooth, shiny | Female | |
| Satin | smooth, shiny | Female | |
| Saturn | Sixth and second largest planet away from the Sun. | Male | |
| Scarlet | Scarlet coloured, deep red | Female | Color |
| Scarlett | Red | Female | English |
| Scout | One dispatched from main body to gather information | Male | Word |
| Selene | after the Greek godess of the moon | Unisex | |
| Shadow | A rough, dark image cast by an object blocking the sun's rays | Female | English |
| Sheba | from Sheba | Female | Hebrew |
| Shelby | From the manor house Willow farm. English surname used more for girls than boys given names.
| Female | English |
| Shiloh | tranquil | Female | Biblical |
| Shredder | | Unisex | Hebrew |
| Sierra | Dark Feminine of Ciaran.
| Female | Spanish |
| Simba | lion | Male | Swahili |
| Simba | from The Lion King | Male | Swahili |
| Simon | he who hears | Male | Hebrew |
| Skylar | eternal life, strength, love and beauty | Female | Spelling |
| Skyler | Dutch, scholar | Male | Spelling |
| Slater | maker of slates | Male | English |
| Smoky | | Unisex | |